PROGNOSIS STRATIFICATION IN BREAST CANCER AND CHARACTERIZATION OF IMMUNOSUPPRESSIVE MICROENVIRONMENT THROUGH A PYRIMIDINE METABOLISM-RELATED SIGNATURE

Pyrimidine metabolism is a hallmark of cancer and will soon become an essential part of cancer therapy.In the tumor microenvironment, cells reprogram pyrimidine metabolism intrinsically and extracellularly, thereby promoting tumorigenesis.Metabolites in pyrimidine metabolism have a significant impact on promoting cancer advancement and modulating i

An interesting case of florid expansile cemento-osseous dysplasia (FECOD) of the maxilla and mandible in a 36-year-old female is being presented.The patient presented for consultation for orthognathic surgery and was unaware of these lesions.Upon clinical and radiographic examination, including cone HEALTHY LUNGS beam computed tomography, massive c

Animal African Trypanosomiasis (AAT) is a debilitating livestock disease prevalent across sub-Saharan Africa, a main cause of which is the protozoan parasite Trypanosoma congolense.In comparison to the well-studied T.brucei, there is a major paucity of knowledge regarding the biology of T.congolense.Here, we use a combination of omics technologies

In this paper, we seek to present the first holistic and frugal business model ever designed to bridge MELATONIN SLEEP the digital divide in Greenfield Africa.Based on an extensive implication in the Connecting Africa and OLPC Projects, Airtel Telecom Group (a Canadian company) partners decided to go one step further in their quest to revamp state

Aphidicolin (APC)-induced chromosomal breakage was analyzed for women representing three generations Adjustable Pedal Mechanism of a single family and carrying a Robertsonian translocation rob(14q21q).Fluorescence in situ hybridization (FISH) analysis confirmed the dicentric constitution of the derived chromosome and indicated the absence of beta-s